- Obstetricians & Gynecologists, Portales - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Off Road Vehicles, Portales
- Off Road Vehicles Parts & Accessories, Portales
- Office Supplies, Equipment & Office Furniture Stores, Portales
- Oil & Gas Additives & Supplies, Portales
- Oil Change & Lubrication, Portales - Auto Oil & Quick Lube
- Oil Field Contractors, Portales
- Oil Industry & Oil Field Equipment & Services, Portales - Oil Companies
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Portales
- Optometrists, Portales - Eye Doctors, Physicians & Surgeons (Optometry)
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- Ornamental Nursery, Portales
- Ornamental Nursery Products, Portales
- Ornamental Nursery Services, Portales
- Orthopedic & Prosthetic Appliances & Shoes, Portales - Orthopedic Shoes
- Other Building Materials & Supplies, Portales
- Outdoor & Lawn & Garden Equipment Repair & Service, Portales
- Outdoor Equipment & Accessories, Portales
- Overhead Door, Portales
- Oxygen & Respiratory Equipment & Supplies, Portales - Oxygen Concentrator, Tank, Machine, etc
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